hrp0097rfc1.3 | Adrenals and HPA Axis | ESPE2023

The effect of storage and temperature on the stability of steroid hormones in dried blood spots

Olthof Anouk , Wickenhagen Wjera , Hillebrand Jacquelien , Boelen Anita , Heijboer Annemieke

Introduction: Monitoring steroid hormone levels of children with endocrine disorders, such as congenital adrenal hyperplasia (CAH) and disorders of sex development (DSD), can be challenging. Dried blood spot (DBS) sampling can be helpful for these patients. DBS sampling is less invasive, easier to sample, and simpler to transport and store compared to venous blood sampling. Additionally, DBS sampling can be done at home at any time of the day, thus improving p...